Functional production of human antibody by the filamentous fungus Aspergillus oryzae

BACKGROUND: Monoclonal antibodies (mAbs) as biopharmaceuticals take a pivotal role in the current therapeutic applications. Generally mammalian cell lines, such as those derived from Chinese hamster ovaries (CHO), are used to produce the recombinant antibody. However, there are still concerns about...

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Vydáno v:Fungal Biol Biotechnol
Hlavní autoři: Huynh, Hung Hiep, Morita, Naoki, Sakamoto, Toshihiro, Katayama, Takuya, Miyakawa, Takuya, Tanokura, Masaru, Chiba, Yasunori, Shinkura, Reiko, Maruyama, Jun-ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257131/
https://ncbi.nlm.nih.gov/pubmed/32514366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40694-020-00098-w
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