Functional production of human antibody by the filamentous fungus Aspergillus oryzae

BACKGROUND: Monoclonal antibodies (mAbs) as biopharmaceuticals take a pivotal role in the current therapeutic applications. Generally mammalian cell lines, such as those derived from Chinese hamster ovaries (CHO), are used to produce the recombinant antibody. However, there are still concerns about...

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Detalhes bibliográficos
Publicado no:Fungal Biol Biotechnol
Main Authors: Huynh, Hung Hiep, Morita, Naoki, Sakamoto, Toshihiro, Katayama, Takuya, Miyakawa, Takuya, Tanokura, Masaru, Chiba, Yasunori, Shinkura, Reiko, Maruyama, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257131/
https://ncbi.nlm.nih.gov/pubmed/32514366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40694-020-00098-w
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