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Per2 attenuates LPS-induced chondrocyte injury through the PTEN/PI3K/Akt signalling pathway

This research aimed to explore the role of period circadian clock 2 (Per2) in the evolution of osteoarthritis (OA) and the relevant mechanisms. Per2 messenger RNA (mRNA) and protein levels were markedly reduced in NHAC-kn cells treated with 5 µg/ml lipopolysaccharide (LPS) for 12 h. Then, pcDNA3.1-P...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Zhao, Yu, Ma, Ding, Dong, Bingchen, Li, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7256672/
https://ncbi.nlm.nih.gov/pubmed/32426819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20200417
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