Bupropion for the Treatment of Apathy in Alzheimer Disease: A Randomized Clinical Trial

IMPORTANCE: Apathy is a frequent neuropsychiatric symptom in dementia of Alzheimer type and negatively affects the disease course and patients’ and caregivers’ quality of life. Effective treatment options are needed. OBJECTIVE: To examine the efficacy and safety of the dopamine and noradrenaline reu...

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Detalles Bibliográficos
Publicado en:JAMA Netw Open
Autores principales: Maier, Franziska, Spottke, Annika, Bach, Jan-Philipp, Bartels, Claudia, Buerger, Katharina, Dodel, Richard, Fellgiebel, Andreas, Fliessbach, Klaus, Frölich, Lutz, Hausner, Lucrezia, Hellmich, Martin, Klöppel, Stefan, Klostermann, Arne, Kornhuber, Johannes, Laske, Christoph, Peters, Oliver, Priller, Josef, Richter-Schmidinger, Tanja, Schneider, Anja, Shah-Hosseini, Kija, Teipel, Stefan, von Arnim, Christine A. F., Wiltfang, Jens, Jessen, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2020
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7256670/
https://ncbi.nlm.nih.gov/pubmed/32463470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.6027
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