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Targeted Myoglobin Delivery as a Strategy for Enhancing the Sensitivity of Hypoxic Cancer Cells to Radiation

The effectiveness of cancer radiotherapy is frequently hindered by the hypoxia of the tumor microenvironment. Direct delivery of oxygen to hypoxic tumor tissues is an attractive strategy to overcome this hypoxia-associated radioresistance. Herein, we report the generation of submicron-sized particle...

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Опубликовано в: :iScience
Главные авторы: Yang, Zaofeng, Heater, Bradley S., Cuddington, Clayton T., Palmer, Andre F., Lee, Marianne M.M., Chan, Michael K.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7256644/
https://ncbi.nlm.nih.gov/pubmed/32464594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101158
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