PSGL-1 inhibits the virion incorporation of SARS-CoV and SARS-CoV-2 spike glycoproteins and impairs virus attachment and infectivity

P-selectin glycoprotein ligand-1 (PSGL-1) is a cell surface glycoprotein that binds to P-, E-, and L-selectins to mediate the tethering and rolling of immune cells on the surface of the endothelium for cell migration into inflamed tissues. PSGL-1 has been identified as an interferon-γ (INF-γ)-regula...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: He, Sijia, Waheed, Abdul A., Hetrick, Brian, Dabbagh, Deemah, Akhrymuk, Ivan V., Kehn-Hall, Kylene, Freed, Eric O., Wu, Yuntao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255790/
https://ncbi.nlm.nih.gov/pubmed/32511349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.01.073387
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