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Mechanism of Notch1-saRNA-1480 reversing androgen sensitivity in human metastatic castration-resistant prostate cancer

The aim of the present study was to explore the mechanism by which Notch1-small activating (sa)RNA restored androgen sensitivity in human metastatic castration-resistant prostate cancer (CRPC). After transfection of Notch1-saRNA-1480 in PC3 cells, the expression of Notch1 and androgen receptor (AR)...

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Detalles Bibliográficos
Publicado en:Int J Mol Med
Main Authors: Ma, Libin, Jiang, Kang, Jiang, Peiwu, He, Han, Chen, Kean, Shao, Jia, Deng, Gang
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255480/
https://ncbi.nlm.nih.gov/pubmed/32626918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4597
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