The JAK2/STAT3 pathway inhibitor, AG490, suppresses the abnormal behavior of keloid fibroblasts in vitro

AG490 is a selective inhibitor of the Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway. The present study examined its effects on the abnormal behavior of human keloid fibroblasts (HKFs) and evaluated its potential use in the treatment of keloids. Hu...

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Veröffentlicht in:Int J Mol Med
Hauptverfasser: Zhou, Ying, Sun, Yuexin, Hou, Wenjun, Ma, Liwen, Tao, Yue, Li, Dan, Xu, Cui, Bao, Jun, Fan, Weixin
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255460/
https://ncbi.nlm.nih.gov/pubmed/32377718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4592
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