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Single-cell analysis reveals fibroblast heterogeneity and myofibroblasts in systemic sclerosis-associated interstitial lung disease

OBJECTIVES: Myofibroblasts are key effector cells in the extracellular matrix remodeling of systemic sclerosis-associated interstitial lung disease (SSc-ILD), however the diversity of fibroblast populations present in the healthy and SSc-ILD lung is unknown, and has prevented the specific study of t...

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Publicado en:Ann Rheum Dis
Autores principales: Valenzi, Eleanor, Bulik, Melissa, Tabib, Tracy, Morse, Christina, Sembrat, John, Bittar, Humberto Trejo, Rojas, Mauricio, Lafyatis, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255436/
https://ncbi.nlm.nih.gov/pubmed/31405848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-214865
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