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Microglial signatures and their role in health and disease

Microglia are the primary innate immune cells in the CNS. In the healthy brain, they exhibit a unique molecular homeostatic ‘signature’, consisting of a specific transcriptional profile and surface protein expression pattern, which differs from that of tissue macrophages. In recent years, there have...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Neurosci
Hauptverfasser: Butovsky, Oleg, Weiner, Howard L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255106/
https://ncbi.nlm.nih.gov/pubmed/30206328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41583-018-0057-5
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