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DR-region of Na(+)/K(+)-ATPase is a target to ameliorate hepatic insulin resistance in obese diabetic mice

Reduced hepatic Na(+)/K(+)-ATPase (NKA) activity and NKAα1 expression are engaged in the pathologies of metabolism diseases. The present study was designed to investigate the potential roles of NKAα1 in hepatic gluconeogenesis and glycogenesis in both hepatocytes and obese diabetic mice. Methods: In...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Sun, Hai-Jian, Cao, Lei, Zhu, Meng-Yuan, Wu, Zhi-Yuan, Shen, Chen-You, Nie, Xiao-Wei, Bian, Jin-Song
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255017/
https://ncbi.nlm.nih.gov/pubmed/32483445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46053
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