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Nucleic Acid Strand Displacement with Synthetic mRNA Inputs in Living Mammalian Cells

Strand displacement reactions are widely used in DNA nanotechnology as a building block for engineering molecular computers and machines. Here, we demonstrate that strand displacement-based probes can be triggered by RNA expressed in mammalian cells, thus taking a step towards adapting the DNA nanot...

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Pubblicato in:ACS Synth Biol
Autori principali: Chatterjee, Gourab, Chen, Yuan-Jyue, Seelig, Georg
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254870/
https://ncbi.nlm.nih.gov/pubmed/30441897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00288
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