Systemic Delivery of Bc12-Targeting siRNA by DNA Nanoparticles Suppresses Cancer Cell Growth

Short interfering RNA (siRNA) is a promising molecular tool for cancer therapy, but its clinical success is limited by the lack of robust in vivo delivery systems. Rationally designed DNA nanoparticles (DNPs) have emerged as facile delivery vehicles because their physicochemical properties can be pr...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Rahman, Mohammad Aminur, Wang, Pengfei, Zhao, Zhixiang, Wang, Dongsheng, Nannapaneni, Sreenivas, Zhang, Chao, Chen, Zhengjia, Griffith, Christopher C., Hurwitz, Selwyn J., Chen, Zhuo G., Ke, Yonggang, Shin, Dong M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254864/
https://ncbi.nlm.nih.gov/pubmed/29076273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201709485
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