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Free Solution Assay Signal Modulation in Variable-Stem-Length Hairpin Aptamers
[Image: see text] Interferometric measurements of free solution assays (FSAs) quantify changes in molecular conformation and hydration upon binding. Here, we demonstrate that aptamer probes designed to undergo varying levels of conformational change upon binding produce corresponding variations in F...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7254501/ https://ncbi.nlm.nih.gov/pubmed/32478218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b04341 |
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