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Secukinumab Therapy for Netherton Syndrome

IMPORTANCE: Netherton syndrome (NS) is a rare, severe genetic disorder of cornification with high morbidity. Treatment for NS has been notoriously difficult. Recent studies showed an upregulated helper T cell (T(H)) 17/interleukin 23 (IL-23) pathway in NS, suggesting the possibility of treatment str...

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Bibliografiske detaljer
Udgivet i:JAMA Dermatol
Main Authors: Luchsinger, Isabelle, Knöpfel, Nicole, Theiler, Martin, Bonnet des Claustres, Mathilde, Barbieux, Claire, Schwieger-Briel, Agnes, Brunner, Corinne, Donghi, Davide, Buettcher, Michael, Meier-Schiesser, Barbara, Hovnanian, Alain, Weibel, Lisa
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254452/
https://ncbi.nlm.nih.gov/pubmed/32459284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2020.1019
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