Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages

BACKGROUND: A bidirectional crosstalk between tumor cells and the surrounding microenvironment contributes to tumor progression and response to therapy. Our previous studies have demonstrated that bcl-2 affects melanoma progression and regulates the tumor microenvironment. The aim of this study was...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Di Martile, Marta, Farini, Valentina, Consonni, Francesca Maria, Trisciuoglio, Daniela, Desideri, Marianna, Valentini, Elisabetta, D'Aguanno, Simona, Tupone, Maria Grazia, Buglioni, Simonetta, Ercolani, Cristiana, Gallo, Enzo, Amadio, Bruno, Terrenato, Irene, Foddai, Maria Laura, Sica, Antonio, Del Bufalo, Donatella
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Basic Tumor Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254128/
https://ncbi.nlm.nih.gov/pubmed/32269145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000489
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