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Traffic jam at the nuclear pore: all roads lead to nucleocytoplasmic transport defects in ALS/FTD

Amyotrophic lateral sclerosis (ALS) is a fatal late-onset neurodegenerative disease that specifically affects the function and survival of spinal and cortical motor neurons. ALS shares many genetic, clinical, and pathological characteristics with frontotemporal dementia (FTD), and these diseases are...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Fallini, Claudia, Khalil, Bilal, Smith, Courtney L., Rossoll, Wilfried
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253339/
https://ncbi.nlm.nih.gov/pubmed/32179176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104835
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