A caveolin binding motif in Na/K-ATPase is required for stem cell differentiation and organogenesis in mammals and C. elegans

Several signaling events have been recognized as essential for regulating cell lineage specification and organogenesis in animals. We find that the gain of an amino-terminal caveolin binding motif (CBM) in the α subunit of the Na/K–adenosine triphosphatase (ATPase) (NKA) is required for the early st...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Wang, Xiaoliang, Cai, Liquan, Xie, Jeffrey X., Cui, Xiaoyu, Zhang, Jue, Wang, Jiayan, Chen, Yiliang, Larre, Isabel, Shapiro, Joseph I., Pierre, Sandrine V., Wu, Dianqing, Zhu, Guo-Zhang, Xie, Zijian
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253156/
https://ncbi.nlm.nih.gov/pubmed/32537485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw5851
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