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Frequency-Specific Optogenetic Deep Brain Stimulation of Subthalamic Nucleus Improves Parkinsonian Motor Behaviors

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for the motor symptoms of Parkinson's disease (PD). However, the neural elements mediating symptom relief are unclear. A previous study concluded that direct optogenetic activation of STN neurons was neither n...

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Опубликовано в: :J Neurosci
Главные авторы: Yu, Chunxiu, Cassar, Isaac R., Sambangi, Jaydeep, Grill, Warren M.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7252487/
https://ncbi.nlm.nih.gov/pubmed/32312888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3071-19.2020
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