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Frequency-Specific Optogenetic Deep Brain Stimulation of Subthalamic Nucleus Improves Parkinsonian Motor Behaviors

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for the motor symptoms of Parkinson's disease (PD). However, the neural elements mediating symptom relief are unclear. A previous study concluded that direct optogenetic activation of STN neurons was neither n...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yu, Chunxiu, Cassar, Isaac R., Sambangi, Jaydeep, Grill, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7252487/
https://ncbi.nlm.nih.gov/pubmed/32312888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3071-19.2020
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