Venlafaxine Stimulates an MMP-9-Dependent Increase in Excitatory/Inhibitory Balance in a Stress Model of Depression

Emerging evidence suggests that there is a reduction in overall cortical excitatory to inhibitory balance in major depressive disorder (MDD), which afflicts ∼14%-20% of individuals. Reduced pyramidal cell arborization occurs with stress and MDD, and may diminish excitatory neurotransmission. Enhance...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Alaiyed, Seham, McCann, Mondona, Mahajan, Gouri, Rajkowska, Grazyna, Stockmeier, Craig A., Kellar, Kenneth J., Wu, Jian Young, Conant, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7252486/
https://ncbi.nlm.nih.gov/pubmed/32269106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2387-19.2020
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