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Random Parametric Perturbations of Gene Regulatory Circuit Uncover State Transitions in Cell Cycle

Many biological processes involve precise cellular state transitions controlled by complex gene regulation. Here, we use budding yeast cell cycle as a model system and explore how a gene regulatory circuit encodes essential information of state transitions. We present a generalized random circuit pe...

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Bibliografske podrobnosti
izdano v:iScience
Main Authors: Katebi, Ataur, Kohar, Vivek, Lu, Mingyang
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251928/
https://ncbi.nlm.nih.gov/pubmed/32450514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101150
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