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Random Parametric Perturbations of Gene Regulatory Circuit Uncover State Transitions in Cell Cycle

Many biological processes involve precise cellular state transitions controlled by complex gene regulation. Here, we use budding yeast cell cycle as a model system and explore how a gene regulatory circuit encodes essential information of state transitions. We present a generalized random circuit pe...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Katebi, Ataur, Kohar, Vivek, Lu, Mingyang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251928/
https://ncbi.nlm.nih.gov/pubmed/32450514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101150
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