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Study of the activation of the PI3K/Akt pathway by the motif of σA and σNS proteins of avian reovirus

The present study was conducted to determine whether avian reovirus (ARV) activates the phosphatidylinositol 3-kinase-dependent Akt (PI3K/Akt) pathway according to the PXXP or YXXXM motifs of σA and σNS proteins. Gene splicing by overlap extension PCR was used to change the PXXP or YXXXM motifs of t...

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Détails bibliographiques
Publié dans:Innate Immun
Auteurs principaux: Xie, Liji, Xie, Zhixun, Wang, Sheng, Deng, Xianwen, Xie, Zhiqin
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251792/
https://ncbi.nlm.nih.gov/pubmed/31779497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425919890648
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