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Conidial Melanin of the Human-Pathogenic Fungus Aspergillus fumigatus Disrupts Cell Autonomous Defenses in Amoebae

The human-pathogenic fungus Aspergillus fumigatus is a ubiquitous saprophyte that causes fatal lung infections in immunocompromised individuals. Following inhalation, conidia are ingested by innate immune cells and can arrest phagolysosome maturation. How this virulence trait could have been selecte...

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發表在:mBio
Main Authors: Ferling, Iuliia, Dunn, Joe Dan, Ferling, Alexander, Soldati, Thierry, Hillmann, Falk
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251208/
https://ncbi.nlm.nih.gov/pubmed/32457245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00862-20
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