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A Gilbert syndrome-associated haplotype protects against fatty liver disease in humanized transgenic mice
UDP-glucuronosyltransferases 1 A (UGT1A) enzymes are capable of detoxifying a broad range of endo- and xenobiotic compounds, which contributes to antioxidative effects, modulation of inflammation and cytoprotection. In the presence of low-function genetic UGT1A variants fibrosis development is incre...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7250928/ https://ncbi.nlm.nih.gov/pubmed/32457304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65481-4 |
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