Diagnostic value of (18)F-FDG-PET to predict the tumour immune status defined by tumoural PD-L1 and CD8(+)tumour-infiltrating lymphocytes in oral squamous cell carcinoma

BACKGROUND: Lately, immune checkpoint proteins, such as programmed death 1 (PD-1) and its ligand-1 (PD-L1), have garnered attention as a new target in oral squamous cell carcinoma (OSCC). Reportedly, fluoro-d-glucose (FDG)-uptake alteration by anti-PD-1 antibody treatment depicts the response in pat...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Togo, Maria, Yokobori, Takehiko, Shimizu, Kimihiro, Handa, Tadashi, Kaira, Kyoichi, Sano, Takaaki, Tsukagoshi, Mariko, Higuchi, Tetsuya, Yokoo, Satoshi, Shirabe, Ken, Oyama, Tetsunari
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250916/
https://ncbi.nlm.nih.gov/pubmed/32238919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0820-z
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