Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo

SWI/SNF (switch/sucrose nonfermenting) complexes regulate transcription through chromatin remodeling and opposing gene silencing by Polycomb group (PcG) proteins. Genes encoding SWI/SNF components are critical for normal development and frequently mutated in human cancer. We characterized the in viv...

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Bibliographic Details
Published in:Sci Adv
Main Authors: van der Vaart, Aniek, Godfrey, Molly, Portegijs, Vincent, van den Heuvel, Sander
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2020
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250657/
https://ncbi.nlm.nih.gov/pubmed/32494730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay3823
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