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Binding Characteristics of Two Oxytocin Variants and Vasopressin at Oxytocin Receptors from Four Primate Species with Different Social Behavior Patterns

A clade of New World monkeys (NWMs) exhibits considerable diversity in both oxytocin (OT) ligand and oxytocin receptor (OTR) structure. Most notable is the variant Pro(8)-OT, with proline instead of leucine at the eighth position, resulting in a rigid bend in the peptide backbone. A higher proportio...

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Publicado en:J Pharmacol Exp Ther
Autores principales: Taylor, Jack H., Schulte, Nancy A., French, Jeffrey A., Toews, Myron L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250472/
https://ncbi.nlm.nih.gov/pubmed/30068728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.250852
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