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Multiple weak interactions between BvgA~P and ptx promoter DNA strongly activate transcription of pertussis toxin genes in Bordetella pertussis

Pertussis toxin is the preeminent virulence factor and major protective antigen produced by Bordetella pertussis, the human respiratory pathogen and etiologic agent of whooping cough. Genes for its synthesis and export are encoded by the 12 kb ptx-ptl operon, which is under the control of the pertus...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Chen, Qing, Boucher, Philip E., Stibitz, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250471/
https://ncbi.nlm.nih.gov/pubmed/32401811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008500
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