TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling

Triggering receptor expressed on myeloid cells 2 (TREM2) serves as an anti-inflammatory receptor, negatively regulating the innate immune response. TREM2 is mainly expressed on dendritic cells and macrophages, the target cells of porcine reproductive and respiratory syndrome virus (PRRSV). Thus, we...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Zhu, Zhenbang, Zhang, Xiaoxiao, Dong, Wenjuan, Wang, Xiaoying, He, Sheng, Zhang, Hui, Wang, Xun, Wei, Ruiping, Chen, Yaosheng, Liu, Xiaohong, Guo, Chunhe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250469/
https://ncbi.nlm.nih.gov/pubmed/32401783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008543
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