Temporal stability of lipid-shelled microbubbles during acoustically-mediated blood-brain barrier opening

Non-invasive blood-brain barrier (BBB) opening using focused ultrasound (FUS) is being tested as a means to locally deliver drugs into the brain. Such FUS therapies require injection of preformed microbubbles, currently used as contrast agents in ultrasound imaging. Although their behavior during ex...

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Detalhes bibliográficos
Publicado no:Front Phys
Main Authors: Pouliopoulos, Antonios N., Jimenez, Daniella A., Frank, Alexander, Robertson, Alexander, Zhang, Lin, Kline-Schoder, Alina R., Bhaskar, Vividha, Harpale, Mitra, Caso, Elizabeth, Papapanou, Nicholas, Anderson, Rachel, Li, Rachel, Konofagou, Elisa E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250395/
https://ncbi.nlm.nih.gov/pubmed/32457896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphy.2020.00137
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