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Screening of BRCA1 variants c.190T>C, 1307delT, g.5331G>A and c.2612C>T in breast cancer patients from North India

The polymorphic variants of BRCA1, which lead to amino acid substitutions, have a known pathogenic role in breast cancer. The present study investigated in North Indian breast cancer patients the association of risk with four reported pathogenic variants of BRCA1: c.190T>C (p.Cys64Arg), 1307delT,...

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Библиографические подробности
Опубликовано в: :Genet Mol Biol
Главные авторы: Kour, Akeen, Sambyal, Vasudha, Guleria, Kamlesh, Singh, Neeti Rajan, Uppal, Manjit Singh, Manjari, Mridu, Sudan, Meena
Формат: Artigo
Язык:Inglês
Опубликовано: Sociedade Brasileira de Genética 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250277/
https://ncbi.nlm.nih.gov/pubmed/32453341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2019-0014
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