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HNF4a transcription is a target of trichloroethylene toxicity in the embryonic mouse heart

In exploration of congenital heart defects produced by TCE, Hepatocyte Nuclear Factor 4 alpha (HNF4a) transcriptional activity was identified as a central component. TCE exposure altered gene transcription in the chick heart in a non-monotonic pattern where only low dose exposure inhibited transcrip...

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Bibliografski detalji
Izdano u:Environ Sci Process Impacts
Glavni autori: Chen, Sheri, Lencinas, Alejandro, Nunez, Martha, Selmin, Ornella I., Runyan, Raymond B.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250168/
https://ncbi.nlm.nih.gov/pubmed/32159184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9em00597h
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