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Compound Heterozygous Variants in Pediatric Cancers: A Systematic Review

A compound heterozygous (CH) variant is a type of germline variant that occurs when each parent donates one alternate allele and these alleles are located at different loci within the same gene. Pathogenic germline variants have been identified for some pediatric cancer types but in most studies, CH...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Miller, Dustin B., Piccolo, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249936/
https://ncbi.nlm.nih.gov/pubmed/32508881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00493
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