Immunogenicity and protective efficacy of a live, oral cholera vaccine formulation stored outside-the-cold-chain for 140 days

BACKGROUND: Cholera, an acute watery diarrhoeal disease caused by Vibrio cholerae serogroup O1 and O139 across the continents. Replacing the existing WHO licensed killed multiple-dose oral cholera vaccines that demand ‘cold chain supply’ at 2–8 °C with a live, single-dose and cold chain-free vaccine...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Immunol
Hauptverfasser: Xian, Tew Hui, Sinniah, Kurunathan, Yean, Chan Yean, Krishnamoorthy, Venkateskumar, Bahari, Mohd Baidi, Ravichandran, Manickam, Prabhakaran, Guruswamy
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249306/
https://ncbi.nlm.nih.gov/pubmed/32450807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-020-00360-1
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