APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway

Hepatocellular carcinoma (HCC) is one of the most prevalent human malignancies worldwide and has high morbidity and mortality. Elucidating the molecular mechanisms underlying HCC recurrence and metastasis is critical to identify new therapeutic targets. This study aimed to determine the roles of ami...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Zhai, Mengying, Yang, Zixia, Zhang, Chenrui, Li, Jinping, Jia, Jing, Zhou, Lingyi, Lu, Rong, Yao, Zhi, Fu, Zheng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249043/
https://ncbi.nlm.nih.gov/pubmed/32457292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2610-1
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