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A novel heterozygous mutation in the HMBS gene in a patient with acute intermittent porphyria and posterior reversible encephalopathy syndrome

Acute intermittent porphyria (AIP) is a rare inherited disorder, which is caused by the partial deficiency of hydroxymethylbilane synthase (HMBS), an enzyme of the heme biosynthetic pathway. Abdominal pain, neuropsychiatric disturbance and neuropathy are the typical manifestations of the disease. Co...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Yang, Yang, Chen, Xiyun, Wu, Huijuan, Peng, Hua, Sun, Wenjing, He, Bin, Yuan, Zhengang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248523/
https://ncbi.nlm.nih.gov/pubmed/32377710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11117
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