The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling

The sympathetic system is involved in the arterial diseases, but its mechanism remains poorly understood. The present study aimed to explore the impact of the sympathetic neurotransmitter norepinephrine (NE) on transforming growth factor (TGF) β signaling and the role of NE in aortic remodeling. Gua...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Hu, Zhipeng, Li, Bowen, Wang, Zhiwei, Hu, Xiaoping, Zhang, Min, Chen, Ruoshi, Wu, Qi, Jia, Fangyuan
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248509/
https://ncbi.nlm.nih.gov/pubmed/32319652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11088
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