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Low penetrance of hearing loss in two Chinese families carrying the mitochondrial tRNA(Ser(UCN)) mutations

Mutations in mitochondrial DNA (mtDNA), especially in mitochondrial 12S rRNA and transfer RNA(tRNA)(Ser(UCN)) genes, are important causes of non-syndromic hearing loss. However, the molecular mechanism underlying mt-tRNA mutations in clinical hearing impairment are not fully understood. The present...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Peng, Wei, Zhong, Yi, Zhao, Xueyan, Yuan, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248462/
https://ncbi.nlm.nih.gov/pubmed/32377700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11100
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