Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis

BACKGROUND: BMP9, originating from the liver, and BMP10 are circulating BMPs that preserve vascular endothelial integrity. We assessed BMP9, BMP10 and soluble endoglin (sEng) levels and their relationships to liver disease severity and associated pulmonary vascular syndromes in a cohort of well-char...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Owen, Nicola E., Alexander, Graeme J., Sen, Sambit, Bunclark, Katherine, Polwarth, Gary, Pepke-Zaba, Joanna, Davenport, Anthony P., Morrell, Nicholas, W., Upton, Paul. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248419/
https://ncbi.nlm.nih.gov/pubmed/32454407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102794
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