Modeling a Nociceptive Neuro-Immune Synapse Activated by ATP and 5-HT in Meninges: Novel Clues on Transduction of Chemical Signals Into Persistent or Rhythmic Neuronal Firing

Extracellular ATP and serotonin (5-HT) are powerful triggers of nociceptive firing in the meninges, a process supporting headache and whose cellular mechanisms are incompletely understood. The current study aimed to develop, with the neurosimulator NEURON, a novel approach to explore in silico the m...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Suleimanova, Alina, Talanov, Max, Gafurov, Oleg, Gafarov, Fail’, Koroleva, Ksenia, Virenque, Anaïs, Noe, Francesco M., Mikhailov, Nikita, Nistri, Andrea, Giniatullin, Rashid
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248338/
https://ncbi.nlm.nih.gov/pubmed/32508598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00135
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