Targeted delivery of chlorogenic acid by mannosylated liposomes to effectively promote the polarization of TAMs for the treatment of glioblastoma

Tumor-associated macrophages (TAMs) generally display an immunosuppressive M2 phenotype and promote tumor progression and metastasis, suggesting their potential value as a target in cancer immunotherapy. Chlorogenic acid (CHA) has been identified as a potent immunomodulator that promotes the polariz...

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Veröffentlicht in:Bioact Mater
Hauptverfasser: Ye, Jun, Yang, Yanfang, Jin, Jing, Ji, Ming, Gao, Yue, Feng, Yu, Wang, Hongliang, Chen, Xiaoguang, Liu, Yuling
Format: Artigo
Sprache:Inglês
Veröffentlicht: KeAi Publishing 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248290/
https://ncbi.nlm.nih.gov/pubmed/32478203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioactmat.2020.05.001
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