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Assay and Isolation of Single Proliferating CD4+ Lymphocytes Using an Automated Microraft Array Platform

OBJECTIVE: While T lymphocytes have been employed as a cancer immunotherapy, the development of effective and specific T-cell-based therapeutics remains challenging. A key obstacle is the difficulty in identifying T cells reactive to cancer-associated antigens. The objective of this research was to...

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Veröffentlicht in:IEEE Trans Biomed Eng
Hauptverfasser: LaBelle, Cody A., Zhang, Raymond J., Armistead, Paul M., Allbritton, Nancy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247929/
https://ncbi.nlm.nih.gov/pubmed/31794384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TBME.2019.2956081
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