TLR-4 Signaling vs. Immune Checkpoints, miRNAs Molecules, Cancer Stem Cells, and Wingless-Signaling Interplay in Glioblastoma Multiforme—Future Perspectives

Toll-like-receptor (TLR) family members were detected in the central nervous system (CNS). TLR occurrence was noticed and widely described in glioblastomamultiforme (GBM) cells. After ligand attachment, TLR-4 reorients domains and dimerizes, activates an intracellular cascade, and promotes further c...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Litak, Jakub, Grochowski, Cezary, Litak, Joanna, Osuchowska, Ida, Gosik, Krzysztof, Radzikowska, Elżbieta, Kamieniak, Piotr, Rolinski, Jacek
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247696/
https://ncbi.nlm.nih.gov/pubmed/32354122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093114
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