Burst, Short, and Sustained Vitamin D(3) Applications Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells

Incorporation of 1,25(OH)(2) vitamin D(3) (vitD(3)) into tissue-engineered scaffolds could aid the healing of critical-sized bone defects. We hypothesize that shorter applications of vitD(3) lead to more osteogenic differentiation of mesenchymal stem cells (MSCs) than a sustained application. To tes...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kelder, Cindy, Hogervorst, Jolanda M.A., Wismeijer, Daniël, Kleverlaan, Cornelis J., de Vries, Teun J., Bakker, Astrid D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247321/
https://ncbi.nlm.nih.gov/pubmed/32366057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093202
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