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How a tailor achieves the perfect fit

Most antigenic peptides that bind stably to a major histocompatibility complex (MHC) I molecule for display to the immune system are approximately the same length, thanks in part to the expert trimming done by endoplasmic reticulum aminopeptidases (ERAPs), the final peptidases in the antigen-present...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Colbert, Jeff D., Rock, Kenneth L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247309/
https://ncbi.nlm.nih.gov/pubmed/32444419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.013868
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