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Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells

BACKGROUND: Nicotinamide N-methyltransferase (NNMT) is highly expressed in several cancers and can regulate cell epigenetic status and various cell metabolism pathways, such as ATP synthesis and cellular stress response. We reported in our previous papers that NNMT overexpression inhibits the apopto...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Yu, Haitao, Zhou, Xi, Wang, Yanzhong, Huang, Xucheng, Yang, Jun, Zeng, Jin, Li, Guoli, Xie, Xinyou, Zhang, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247246/
https://ncbi.nlm.nih.gov/pubmed/32489327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01279-8
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