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Protective effects of rolipram on endotoxic cardiac dysfunction via inhibition of the inflammatory response in cardiac fibroblasts

BACKGROUND: Cardiac fibroblasts, regarded as the immunomodulatory hub of the heart, have been thought to play an important role during sepsis-induced cardiomyopathy (SIC). However, the detailed molecular mechanism and targeted therapies for SIC are still lacking. Therefore, we sought to investigate...

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Detalhes bibliográficos
Publicado no:BMC Cardiovasc Disord
Main Authors: Ji, Jingjing, Liu, Zhifeng, Hong, Xinxin, Liu, Zheying, Gao, Jinghua, Liu, Jinghua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247226/
https://ncbi.nlm.nih.gov/pubmed/32448150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-020-01529-7
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