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Methotrexate use and NAD(+)/NADH metabolism in psoriatic keratinocytes
Methotrexate inhibits tetrahydrofolic acid production and influences mitochondrial oxygen uptake and activity of several enzymes in the respiratory chain reactions, which utilize nicotinamide adenine dinucleotide-linked (NAD-linked) substrates. Hyperproliferation of keratinocytes in psoriasis requir...
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| Publicado no: | Postepy Dermatol Alergol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Termedia Publishing House
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247064/ https://ncbi.nlm.nih.gov/pubmed/32467678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ada.2020.93379 |
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