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Therapeutic Targeting of the General RNA Polymerase II Transcription Machinery
Inhibitors targeting the general RNA polymerase II (RNAPII) transcription machinery are candidate therapeutics in cancer and other complex diseases. Here, we review the molecular targets and mechanisms of action of these compounds, framing them within the steps of RNAPII transcription. We discuss th...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7246882/ https://ncbi.nlm.nih.gov/pubmed/32397434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093354 |
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