Pathogenic Roles of Autoantibodies and Aberrant Epigenetic Regulation of Immune and Connective Tissue Cells in the Tissue Fibrosis of Patients with Systemic Sclerosis

Systemic sclerosis (SSc) is a multi-system autoimmune disease with tissue fibrosis prominent in the skin and lung. In this review, we briefly describe the autoimmune features (mainly autoantibody production and cytokine profiles) and the potential pathogenic contributors including genetic/epigenetic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Tsai, Chang-Youh, Hsieh, Song-Chou, Wu, Tsai-Hung, Li, Ko-Jen, Shen, Chieh-Yu, Liao, Hsien-Tzung, Wu, Cheng-Han, Kuo, Yu-Min, Lu, Cheng-Shiun, Yu, Chia-Li
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246753/
https://ncbi.nlm.nih.gov/pubmed/32349208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093069
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