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Poly(lysine) Dendrimers Form Complexes with siRNA and Provide Its Efficient Uptake by Myeloid Cells: Model Studies for Therapeutic Nucleic Acid Delivery

The disruption of the cellular pathways of protein biosynthesis through the mechanism of RNA interference has been recognized as a tool of great diagnostic and therapeutic significance. However, in order to fully exploit the potential of this phenomenon, efficient and safe carriers capable of overco...

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Publicat a:Int J Mol Sci
Autors principals: Gorzkiewicz, Michał, Kopeć, Olga, Janaszewska, Anna, Konopka, Małgorzata, Pędziwiatr-Werbicka, Elżbieta, Tarasenko, Irina I., Bezrodnyi, Valeriy V., Neelov, Igor M., Klajnert-Maculewicz, Barbara
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246632/
https://ncbi.nlm.nih.gov/pubmed/32365579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093138
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